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Deoxycholic acid has been studied in randomised trials and a systematic review found it does reduce submental fat, though the reviewers also flagged potential industry bias in the published studies

Most recently, in October 2024, an updated ASA-led multisociety clinical practice guidance shifted toward a risk-stratified approach, highlighting prolonged fasting and optional POCUS evaluation rather than universal discontinuation of GLP-1 RAs [10]

To view a copy of this licence, visit About this article Cite this article Kumar, R., Sahay, N

This may involve acquiring a new supply of medication through our comprehensive loss program, which includes dietitian consultations and fitness training