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Decades of diabetes research and the development of semaglutide have turned what many thought was impossible into a reality: delivering a peptide that could regulate specific biological functions within the body, in a pill for type 2 diabetes that mimics a naturally occurring hormone to lower blood sugar

A non-parametric bootstrapping method with 5,000 simulations was used to assess the indirect effects, considering an effect significant if the 95% confidence interval did not include zero