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In clinical trials, people taking Contrave lost an average of about 8% of their initial body weight after 56 weeks, compared to less than 2% in those who took a placebo (inactive medicine)
It is approved for UK use, but it is not currently available through the NHS
However, mood changes are not officially recognised as a side effect in the MHRA-approved product literature
Clinically, common side effects echo those of other GLP-1 agonists, including gastrointestinal issues such as nausea or diarrhea
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