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Author Contributions M Brines designed the trial, analyzed data and wrote the manuscript
Macro-B12 is commonly defined as the fraction of B12 removed by precipitation with polyethylene glycol (PEG)
B12 IM injections are often recommended for individuals with conditions that affect B12 absorption, such as pernicious anemia, atrophic gastritis, or those who have undergone certain gastrointestinal surgeries
For these patients, methylated B12 is profoundly more effective
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