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Consult with a health provider: These medications require a prescription, so the first step is to consult a physician who will assess your health, weight loss goals, and medical history to determine if semaglutide or tirzepatide are suitable options for you

A concentration step is often included before immunodepletion, generating two fractions: a concentrated protein fraction for immunodepletion and a low-molecular-weight fraction typically discarded (Fig

This ratio worsens considerably when caloric surplus exceeds 300-500 calories above maintenance

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