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Significant alterations in reproductive hormones were observed in SCH patients, including reduced LH levels (SMD = 0.20
Its defining structural feature is the gamma-glutamyl linkage: the glutamate residue is joined through its side-chain carboxyl rather than the usual alpha-peptide bond, which makes the molecule resistant to most intracellular peptidases and means it is cleaved almost exclusively by gamma-glutamyl transpeptidase at the outer cell surface (Zhang, Forman and Choi, Methods in Enzymology, 2005)
[Glutathione S-transferase] [PMID: 10503468] Laboratory literature summary: [Glutathione S-transferase]
Patients should be aware that GLP-1 medications are initiated and monitored within specialist or primary care diabetes services
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