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In human skin fibroblasts, Nrf2-driven antioxidant enzyme expression translated into: Reduced intracellular ROS Improved mitochondrial membrane potential Protection against senescence-associated cell damage [36] In human gingival and periodontal stem cells, Epitalon significantly reduced aging biomarkers such as p16 and p21, decreased ROS levels, and preserved mitochondrial function, even under stress [42]

Iodine Iodine is a mineral that is necessary for proper production of thyroid hormone, which is crucial for brain development in the developing fetus

The two compounds operate on different timelines

Figure 6 Figure 7 3.5.4 Subgroup analysis of the effects of different types of exercise combined with tDCS on cognitive function in older adults Subgroup analysis revealed that different exercise types significantly modulated the intervention effect of tDCS ( p = 0.0015)