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As previously reported, mitophagy dysfunction is closely associated with activation of NLRP3 inflammasome 19,38,39
Clinical context: SURMOUNT-1 showed tirzepatide produced an average of 22.5% body weight loss at 72 weeks at the highest dose
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Phentermine may reduce appetite more quickly for some patients, while semaglutide often builds more gradually as dosing is adjusted for tolerability
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