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129 In studies using 3T3-L1 cells, resveratrol treatment significantly decreased lipid accumulation, down-regulated the expression of C/EBP, LPL, FAS, and SREBP-1c through activation of AMPK, 130 decreased phosphorylation of MAPKs, and reduced Rb phosphorylation, 131 suppressed hormonal-induced AKT activation and cell proliferation, and inhibited cell entry into the S phase and the S to the G2/M phase transition
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E.Van't VeerP.et al (2013)
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