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Medical Writing, Editorial, and Other Assistance Gabrielle Dardis, PhD, and Matt Fitzpatrick, PhD, of RTI Health Solutions, a subsidiary of RTI International, a nonprofit organization that conducts work for government, public, and private organizations, including pharmaceutical companies, provided medical writing support, and John Forbes of RTI Health Solutions provided medical editing support with funding from Bayer AG during manuscript development
According to the MHRA's latest guidance, while occurrences are rare, there have been reports of severe, necrotizing, and even fatal pancreatitis associated with GLP-1 and GIP receptor agonists
PMID 21631324
So DiMarchi started creating drugs that targeted both GLP-1 and glucagon receptors
![Structure of [ 3 H]liraglutide (top) and the GLP-1 receptor agonists](https://www.researchgate.net/publication/45650716/figure/fig2/AS:667822585806848@1536232720030/Structure-of-3-Hliraglutide-top-and-the-GLP-1-receptor-agonists-liraglutide-and.png)
