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Maczurek, et al., Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimers disease, Advance Drug Delivery Review , 2008;60(13-14):1463-70 2
Activation of NRF2 prevents tissue damage under pathological conditions 59
Fe 3+ absorbed into the cell is located in the endosomes and is reduced to ferrous iron (Fe 2+ ) by transmembrane epidermal antigen of prostate 3 (STEAP3) [70]
Finally, we note that the model predicts modest decreases in the rate of the DNA methylation reaction (vDNMT) and this is consistent with the reported global DNA hypomethylation seen in autistic children [73]
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