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Abbreviations CKD: Chronic kidney disease TECs: Tubular epithelial cells UUO: Unilateral ureteral obstruction IRI: Including ischemia-reperfusion injury Fer-1: Ferrostatin-1 GPX4: Glutathione peroxidase 4 ACSL4: Acyl-CoA synthetase long-chain family 4 LPCAT3: Lysophosphatidylcholine acyltransferase 3 TFRC: Transferrin receptor protein 1 DMT1: Divalent metal transporter 1 FPN: Ferroportin CTGF: Connective tissue growth factor PDGFB: Platelet-derived growth factor subunit b FGF2: Fibroblast growth factor 2 4-HNE: 4-hydroxynonenal MDA: Malondialdehyde References Webster AC, Nagler EV, Morton RL, Masson P
Here, the Toronto Functional Medicine Centre explains how IV therapy and oral supplementation with glutathione could help offset premature skin aging, while promoting brain and cellular detoxification
This subsection emphasizes the broader and more holistic mechanisms by which TCM formulations synergize with 5-ASA
doi:10.1210/en.2002-220670
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