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The tripeptide modulates over 4,000 human genes (31.2% of the genome) and plasma levels decline from approximately 200 ng/mL at age 20 to less than half by age 60 (Pickart & Margolina, 2018)
Micioni Di Bonaventura, E., Botticelli, L., Del Bello, F., Giorgioni, G., Piergentili, A., Quaglia, W., Romano, A., Gaetani, S., Micioni Di Bonaventura, M
Cesco et al., 2012)
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