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But injectable delivery is more potent for systemic anti-aging effects it reaches every tissue in the body, not just the surface layers of skin where a cream is applied
Who Should Use GLP-1 Supplements: Eligibility and Safety Considerations GLP-1 supplementation is most appropriate for adults with BMI 27 kg/m (with weight-related comorbidity) or BMI 30 kg/m without comorbidity, or those with type 2 diabetes
Note: Lemonaid Healths parent company, 23andMe, filed for Chapter 11 bankruptcy in March 2025
Research also suggests that a better quality dietary lifestyle can help reduce the severity of GLP-1 side effects more broadly, with complementary nutritional strategies shown to address gastrointestinal adverse effects, support lean mass preservation, and improve long-term adherence
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