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This therapy has big benefits
But the study authors named it explicitly as an off-target activity they are working to engineer out, and even speculated that some of the glucose-tolerance benefit might come from it
A 2021 rat study reported 38.4% oral bioavailability
A 2018 study reported that administering 5-Amino-1MQ to diet-induced obese mice, at the dose defined in the study protocol over an 11-day period, was associated with reduced body weight, decreased adipose mass, and lowered plasma cholesterol without reduced food intake, pointing to altered energy handling
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