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His short-term memory issues made him concerned that he had an early form of dementia

Jastreboff, MD, PhD Director, Weight Management & Obesity Prevention Yale School of Medicine, New Haven, Connecticut Professor Ania Jastreboff has been a principal investigator for pivotal GLP3 clinical trials, including the landmark phase 2 obesity study published in the New England Journal of Medicine

First, the vote was nonbinding: the FDA makes the final rulemaking decision and has previously declined to follow advisory committee recommendations

Importantly, food intake remained unchanged in treated animals, suggesting the compound's effects relate to energy expenditure pathways rather than appetite