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-catenin could interact with TCF/LEF transcription factors to upregulate the expression of oncogenes such as MYC, CCND1, and LGR5 [111], which are key drivers of cell cycle progression and tumor proliferation
The American College of Physicians and American Diabetes Association emphasize that treatment decisions should be individualized based on patient preferences, comorbidities, and clinical circumstances, with shared decision-making between patients and healthcare providers
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