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Donors (10 females, 14 males) were on average 48 years old (range 1961) with a BMI of 28 (range 2137)

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Taken together, our data support the view that mitochondrial activation is an early, conserved, and functionally integrated feature of neuronal differentiation, during which neurons establish a metabolically flexible phenotype combining sustained glycolytic activity with enhanced OXPHOS

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