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For weight management or blood sugar concerns, a clinician may recommend lifestyle changes, testing, prescription medicine, or referral to a specialist rather than relying on an unproven patch
One study enrolled older adult inpatients with depression without an explicitly stated diagnostic framework
Pancreatitis is another potential adverse effect that can be serious
The efficacy and safety of tirzepatide, with a special focus on cardiovascular safety, were investigated in the 52-week SURPASS-4 trial testing tirzepatide versus insulin glargine in adults with T2D and a high cardiovascular risk under inadequate glycemic control at baseline on one to three oral glucose-lowering medications (metformin, sulfonylurea, SGLT-2 inhibitor) (74)
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