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The preclinical foundation is strong, particularly for BPC-157 and thymosin beta-4, but the gap between animal evidence and clinical application can only be bridged through rigorous controlled studies in human fracture patients
The animal data, however, has been remarkably consistent and genuinely promising: Tendon and ligament healing : In rat models of Achilles tendon rupture, animals treated with BPC-157 showed significantly improved biomechanical outcomes (including greater failure load and tissue stiffness) within 10 to 14 days compared to untreated controls
All experiments were performed in triplicate
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