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This connection between the gut & pancreatic islets may be responsible for ~50% of postprandial insulin release (Perley & Kipnis, J Clin Invest 46:1954-1962
Common side effects of psyllium husk include stomach cramps, constipation, diarrhea, increased gas or bloating, nausea and temporary weight gain
N Engl J Med 384(11):9891002 Davies M, Frch L, Jeppesen OK et al (2021) Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial
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