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Most patients report that the area treated continues to look improved even after the filler has been fully resorbed

Here's the realistic timeline: Phase 3 trials (AMAZE program): - AMAZE 1 (obesity) started February 2026, enrolling ~1,150 participants - Primary completion estimated: June 2029 - Phase 3 in T2D also being planned following the ADA 2026 data US FDA approval (projected): Q4 2030 at the earliest (GlobalData estimate) EU EMA approval (projected): Q1 2031 at the earliest Bulgaria and Eastern Europe: Typically 612 months after EMA approval for market access, depending on national reimbursement negotiations

For researchers new to this space, our complete guide to research peptides provides useful foundational context for understanding where this compound fits within the broader synthetic peptide research landscape

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