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However it was not clear whether ROS was produced by Bd as a virulence mechanism, as seen in many phytopathogenic fungi (50, 51), or alternatively produced by the host as a response to infection (52), or associated membrane damage (22)
This multi-receptor targeting approach potentially offers a more comprehensive metabolic effect by enhancing insulin sensitivity, reducing hunger, and increasing energy expenditure through glucagon activity
They also slow the rate of gastric emptying, leading to a more gradual release of stomach contents and a longer duration of feeling full
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