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Numerous studies have also shown how important the portal glucose sensor is in maintaining glucose homeostasis and how GLP- 1 receptors are related to portal glucose sensing, with GLP- 1 being required for portal glucose to trigger the insulin response

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The high dose was more effective than the low dose, and both positively reduced DNA damage by reducing DNA tail and DNA moment

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They found that in the area postrema, a brain region that includes appetite-related circuits, the extent of increase in levels of cyclic adenosine monophosphate (cAMP), a signal-transducing molecule, determines the weight-loss effect of semaglutide

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