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Specifically, Clostridium scindens (now known as Lachnoclostridium scindens ) is a pivotal functional species that mediates the conversion of primary bile acids into secondary bile acids via 7-dehydroxylation, thereby maintaining intestinal homeostasis and barrier integrity 181
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The primary objective of this systematic review is to provide an updated and comprehensive evaluation of the efficacy and safety of GLP-1 RAs in the management of IIH
It's worth noting that type 2 diabetes itself is associated with an increased fracture risk despite often normal or higher bone mineral density, which may complicate the interpretation of bone health outcomes in this population
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