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5 Conclusions In conclusion, the present study, which evaluated oral semaglutide at a daily dose of 14 mg for the treatment of obesity in adults without diabetes, demonstrated substantial interindividual variability in weight loss response in a real-world setting

Many women find that dietary changes alone, or combined with insulin, effectively control glucose during pregnancy

Similar findings were observed in the 104-week STEP 5 study

Some research protocols account for this by using comparatively lower dosing ranges in female study cohorts, reflecting a generally increased sensitivity to IGF-1 receptor activation a pattern also documented in broader growth hormone axis research, not unique to IGF-1 LR3 specifically