Studies limited to paediatric populations, non-English publications, preclinical investigations without clinical relevance, or reports lacking meaningful safety data were excluded
Figure 1 4.1.1 Cardiovascular outcomes in SGLT2 inhibitors: safety studies The EMPA-REG OUTCOME trial, which included 7020 patients with T2DM, was the first to demonstrate the cardiovascular protective effects of empagliflozin (54, 56)
Uhles S, Wang H, Bnardeau A, Prummer M, Brecheisen M, Sewing S, Tobalina L, Bosco D, Wollheim CB, Migliorini C
The morning routine advantage Adherence research consistently shows that medications tied to morning routines have higher compliance rates