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Step 3: NICE Assessment (For NHS Use) If MHRA approval is granted, the medicine may then be assessed by NICE to determine: Cost-effectiveness Eligible patient groups Prescribing criteria Whether the NHS funds it This stage mainly affects NHS availability, but private prescribing decisions may differ depending on the product licence

The most common side-effects were gastrointestinal issues, such as nausea or diarrhoea

When you drop below it, compensatory mechanisms kick in: increased hunger signals, reduced energy expenditure, stronger cravings for calorie-dense foods

Ozone therapy effects on IgE, HLA-DR and Glutathione antioxidant pathway