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It has been shown to reduce the risk of major adverse cardiovascular events, such as heart attack and stroke, in clinical trials

This blog will explore the role of GLP-1s in metabolic health, their potential when microdosed, their intersection with autoimmune diseases, and their impact on inflammation through a functional medicine lens

It acts primarily on the central nervous system, particularly targeting melanocortin receptors MC3R and MC4R, which are involved in sexual arousal and desire

In December 2025, Eli Lilly released Phase 3 clinical trial results showing that retatrutide produced an average weight loss of 28.7% of body weight at 68 weeks