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GLP-1 receptor expression in human internal thoracic arteries is dependent on low-grade inflammation potentially explaining the cardiovascular protective effect of GLP1-R agonists
In a phase 2 trial, 43% to 100% of participants experienced at least a 50% reduction in liver fat, and 32% to 93% achieved at least a 70% reduction
These findings were confirmed by the observational analysis , which also reported increased musculoskeletal issues such as arthralgias and arthritis
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