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Future studies employing complementary models and clinical samples will be necessary to further substantiate the translational relevance of our findings

Avoid high-sugar, high-fat foods, which can slow progress and increase side effects like nausea

Prominent in neurons, but not glial cells, GIP synthesis is more distributed in the CNS compared to GLP-1 and was identified in the hippocampal CA1-3, granule cell layer and neurogenic niche of the dentate gyrus, thalamus, cerebral cortex, cerebellum (Purkinje cells) and brainstem

Semaglutide has been shown to reduce CV risk in people with T2D and established or high risk of CV disease