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About this article Cite this article Lequan, Q., Yanan, F., Xianda, Z
Although oxidative stress was defined originally as a balance between oxidants and antioxidants systems, an equilibrium among antioxidant strategies is needed to avoid the generation of oxidants and ROS (Mari et al., 2010)
They concluded that while GHK-Cu does demonstrate anti-wrinkle effects in cellular studies, "there is a surprising absence of clinical studies using them." The review identified skin permeation as the central challenge: GHK's high aqueous solubility and low partition coefficient work against transdermal absorption
Probst L, Dchert J, Schenk B, Fulda S
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