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Considering that follicles close to the OE lesion tissues exhibit higher total iron levels and lower oocyte retrieval rates than follicles in healthy ovaries [28], iron overload in the OE may impair oocyte maturation and function by affecting granulosa cells close to the lesion and further mediate the release of abnormal exosomes of granulosa cells

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Amidst these stromal alterations are accumulations of pigment-laden macrophages that can assume a globular architecture similar to animal-type melanoma but lack nuclear atypia

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