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We performed an NMA 71 for all outcomes listed above to examine differences across individual OMMs and their effects on primary and secondary endpoints

Oikonomou E, Vaid A, Holste G, Coppi A, McNamara R, Baloescu C, Krumholz H , Wang Z, Apakama D, Nadkarni G, Khera R

This raises the minimum risk-adjusted value each program needs to generate to counteract their cost to develop, meaning portfolios with many lower forecast value assets face disproportionate pressure unless they are clearly differentiated or strategically essential