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J Ethnopharmacol (2007) 111:63640
Methylmalonic acid is a more sensitive marker of functional B12 status Complete blood count (CBC): Establishes baseline red blood cell parameters for monitoring anemia development Iron panel (ferritin, serum iron, TIBC): Ferritin below 30 ng/mL suggests depleted stores even with normal hemoglobin Comprehensive metabolic panel: Includes calcium, magnesium (though serum magnesium is imperfect), and kidney function RBC magnesium: More accurate than serum magnesium
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Following the positive REDEFINE 1 Phase 3 data (published June 2025, PMID: 40544433), Novo Nordisk announced plans to file regulatory applications for CagriSema for obesity in the United States (FDA), European Union (EMA), and other major markets in 20252026
