When the endogenous antioxidant system cannot remove free radicals appropriately, oxidative stress, the accumulation of such free radicals, accelerates a variety of disease conditions, such as diabetes and its complications, cancer, and neuronal disorders
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Author FC was employed by Henan ANIMIC Biotechnology Co., Ltd., China
It emphasizes that mild or transient heat stress primarily activates protective proteostasis-maintaining responses, whereas sustained or severe heat stress may exceed the compensatory capacity of the molecular chaperone system, thus promoting oxidative stress, apoptosis, and impaired spermatogenesis