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More specifically, pyridoxine is converted to pyridoxal 5-phosphate in the body, which is an important coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid

This is not a complete list of drugs that can interact with Synthroid

The evidence base is strongest in EPP

Altern Med Rev 6(3):248271 Pawlowska E, Szczepanska J, Blasiak J (2019) Pro- and antioxidant effects of vitamin C in Cancer in correspondence to its dietary and pharmacological concentrations