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534 Furthermore, PRRs regulate various innate immune cells, including innate lymphoid cells, pDCs, Kupffer cells, and macrophages, to secrete cytokines and chemokines that further recruit cells, sustain inflammation, and enhance profibrotic responses

It is investigational (not FDA-approved on its own)

After quality control, we identified 47,413 cases of CAD (31,127 in men, 16,286 in women), 7961 cases of ischemic stroke (4915 in men, 3046 in women), 12,926 cases of heart failure (8456 in men, 4470 in women), and 18,382 cases of AF (12,260 in men, 6122 in women)