For example, clinical trials of semaglutide and tirzepatide report dyspepsia occurring in approximately 3-9% of patients, with GERD and belching/eructation also noted in some product labels
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In the SURMOUNT-1 study, a phase 3 clinical trial in obese patients, randomized participants in a 1:1:1:1 ratio to tirzepatide (5, 10, 15 mg) or placebo over 72 weeks, significant weight reductions were observed at 72 weeks: 15.0% for 5 mg, 19.5% for 10 mg, 20.9% for 15 mg, compared to 3.1% for placebo [18]
Navigating the Risks: When Appetite Suppression Meets Binge Eating Recovery Heres the thing, for a lot of people I see in my nutrition therapy clinic, starting a GLP-1 jabs feels like finally switching off the mental chatter around food and finally being able to go around their day and food like a normal person