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3 RGN-259 Phase 3 Trial in Neurotrophic Keratopathy Sosne et al., International Journal of Molecular Sciences (2022) This Phase 3 randomized, placebo-controlled, double-masked clinical trial evaluated topical 0.1% RGN-259 (full-length recombinant T4 ophthalmic solution) in patients with neurotrophic keratopathy

The FDA's bulk substance framework for compounding pharmacies established under the 2013 Drug Quality and Security Act divides peptides into three categories relevant to 503A/503B compounding: Category 1 : Affirmed for compounding

Circulation 137 , 455463 (2018)