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If this translates clinically, it could explain signals across alcohol, nicotine, opioids, and other substances
29 The randomized, double-blind study enrolled 1,864 participants with a mean baseline A1C of 8.3% and BMI of 32.5
For many people, cost and access shape the real-world decision as much as potency
High gastrointestinal discontinuation rates exceeding 50% across all doses, combined with liver safety signals in early studies, ultimately led Pfizer to discontinue danugliprons development in April 2025
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