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Additionally, the phase 2 MOMENTUM clinical trial of pemvidutide (a dual GLP-1/GCG agonist) showed that only 21.9% of WL was attributable to reductions in lean mass at 48 weeks (overall WL 10.315.6% across doses) [64]

However, many patients require treatment more frequently than current guidelines suggest

Diabetes Care 47 , 17181730 (2024)

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