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The interstitium is with intact blood vessels and Leydig cells ( IS )
It takes some time to lose weight with semaglutide, as most patients do not notice the effects of semaglutide therapy until around 12 weeks of treatment
Based on cohort studies of patients with obesity (irrespective of diabetes status) who were newly started on tirzepatide or semaglutide, tirzepatide is associated with significantly more weight loss than semaglutide [102]
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