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The trial tested multiple dose levels over 48 weeks, and the headline result, up to 24.2% body weight reduction at the highest dose, grabbed international attention

Currently, there is no established causal relationship between Ozempic and depression based on clinical trial data and regulatory assessments

Participants who experienced changes in concomitant oral antidiabetic drugs during the observation period were excluded, which precluded assessment of the impact of such changes

Clinical translation of the developed PLGA-based nanosystems encapsulating conventional drugs and/or bioactive phytochemicals remains a challenge due to limited clinical trials validating the safety and efficacy of PLGA nano-systems