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Exposure to Certain Medications: Drugs that are folate antagonists, such as methotrexate (used in chemotherapy), can deplete CNS folate
When folate supply to the rapidly dividing cells of the bone marrow is inadequate, blood cell division is reduced, resulting in fewer but larger red blood cells
No associations were observed for other brain volume measures (total brain, white matter and hippocampus), white matter hyperintensity volume or MRI markers of small vessel disease (fractional anisotropy and mean diffusivity)
Cloudiness or visible particles indicate contamination or precipitation
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