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It is most relevant during GLP-1 use or caloric deficit, when fatigue is part of the picture, or when progress stalls after a clean first month
Current Medicinal Chemistry , 19 (1), 126132
Before human translation, essential parameters to define: optimal dosing, infusion/administration route, frequency, biomarkers to monitor (senescent cell burden, inflammatory cytokines, organ function), long-term follow-up for adverse outcomes (especially tumour risk)
Recommendations are based on provider evaluation and clinical appropriateness
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