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Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression
That's the threshold that changes the conversation
The compound therefore functions as a positive modulator of an existing growth factor system rather than as an independent agonist, which is the proposed explanation for its reported potency: it amplifies a signal already present rather than supplying a new one
Insights into the role of copper in neurodegenerative diseases and the therapeutic potential of natural compounds
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