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It rarely occurs to physicians to consider disturbances of water distribution in problems such as chronic fatigue, fibromyalgia, sleep disturbances, frequent urination, slow bladder emptying, anxiety, paresthesia, movement disorders, the tunnel syndromes, or even slowed thinking, but "intracellular fatigue" leading to over-hydration is probably the central problem in these, and many other degenerative and inflammatory problems
If anything, making something enjoyable to take consistently actually improves effectiveness over time, because compliance is everything. I can confirm the fun flavors have made me compliant with my supplement routine, but more on that ahead
Other oral tirzepatide alternatives include pills like metformin and Rybelsus