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NICE guidance (NG100) recommends disease-modifying antirheumatic drugs (DMARDs) as standard care, with methotrexate as first-line therapy
A minority of trial participants discontinued treatment due to gastrointestinal events, underscoring the importance of appropriate dose titration and proactive symptom management
428 Similarly, AI has been applied in DKD screening and management, as shown by the Minuteful Kidney system
This approach mirrors how anti-obesity medications are used in clinical practice, where long-term maintenance therapy prevents weight regain
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