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GLP-1Rs are widely distributed in several cells, such as islet cells (especially -cells of the pancreas), endothelial cells, neurons, adipocytes, keratinocytes, lymphocytes, hepatocytes, smooth muscle cells, myocytes, Brunners glands in the duodenum, and myenteric plexus neurons in the gut 31,32,33,34
Seek immediate medical attention for severe persistent abdominal pain, vomiting or diarrhea lasting over 2448 hours, signs of gallbladder disease, hypoglycemia symptoms, or allergic reactions
Patients losing significant amounts of weight over relatively short periods might potentially notice changes in temperature perception
Eur Heart J 31(6):737746 Ahlqvist E, Prasad RB, Groop L (2020) Subtypes of type 2 diabetes determined from clinical parameters
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